A variable disorder that is marked especially by amenorrhea, hirsutism, obesity, infertility, and ovarian enlargement and is usually initiated by an elevated level of luteinizing hormone, androgen, or estrogen which results in an abnormal cycle of gonadotropin release by the pituitary gland —abbreviation PCOS — called also polycystic ovary disease, polycystic ovary syndrome, polycystic ovary disease, Stein-Leventhal syndrome.